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History of 'The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and Inducible Expression of Intestinal Detoxification and Glutathione Biosynthetic Enzymes'

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The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and Inducible Expression of Intestinal Detoxification and Glutathione Biosynthetic Enzymes

Author(s): McMahon M, K Itoh, M Yamamoto, S Chanas, C Henderson, L McLellan, CR Wolf, C Cavin, J Hayes
Published in: Cancer Research. Apr 15, 2001
Volume: 61 Issue: 1 Pages: 3299-3307
Free Article: http://cancerres.aacrjournals.org/cgi/content/full/61/8/3299

Cancer research has shown that edible plants might be helpful as part of future cancer treatment regimens. It has been found that each particular patient is different, however, as each person has a different level of several components in their digestive tract.

To test this hypothesis, researchers examined the small intestines of various ten week old male mice. With the evidence found in this experiment, researchers might be a step closer to determining the enzymes which a person must have in order for the edible plants to be used as a possible form of treatment.

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