Moringa Gateway

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Author(s): Lockett CT, CC Calvert, LE Grivetti
Published in: International Journal of Food Sciences and Nutrition.   Jun 20, 2000
51 1 195-208
http://www.ingentaconnect.com/content/apl/cijf/2000/00000051/00000003/art00008

Northeastern Nigeria is home to the Fulani people. Two of the settled villages in which they live are Amtasa and Dongo. Authors of this article aimed to evaluate the nutritional value of the edible plants in the region.

The main author of this paper was escorted through both villages by two assistant/translators. He spoke with small groups of elderly villagers who were knowledgable of the edible plants within a five mile radius of each village, during his visit. Once a comprehensive list of such plants was created, households in each village were surveyed as to their usage of each plant. Within Amtasa two hundred and fifty households were surveyed, while in Dongo there were merely one hundred households which participated.

The plants which were used in the survey were then taken to the laboratory to be studied further. After such investigations into the nutritional values of each, researchers found that several plants provided a large amount of nutrition to those who ate it. The Moringa oleifera, for example, was found to contain protein, fat, calcium, copper, iron and zinc.


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Author(s): LJ Fuglie
Published in: ECHOs Technical Network Site.   Jun 8, 2000
http://www.echotech.org/network/modules.php?name=News&file=article&sid=194

Moringa oleifera leaves have many practical uses. Agriculturally the leaves can be used as or in combination with livestock feed, a manure or plant growth hormone spray for other plants or even as part of a water treatment plan. This article outlines an efficient "how to" guide for each use of the leaves through the suggestions of Nikolaus and Gabriele Foidl in Nicaragua in their work with the Moringa.


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Chemistry and Pharmacology of Moringa Oleifera LAM and M. Concanensis Nimo

Author(s): Jadhav S.L., Sharma S.R., Pal S.C., Kasture S.B., and Kasture V.S
Published in: Indian Drugs .   Mar 1, 2000
37 3 139-144

Moringa Oleifera Lam is indigenous to the sub-Himalayan region and cultivated in India and Burma. A second species of Moringa is M. Concanensis. This abstract focuses on the first species, Moringa Oleifera.
All parts of the plant are used in traditional Ayurvedic medicine. This article is an attempt to examine the chemical and pharmacological usefulness of the plant for various medicinal treatments. Roots are utilized to treat fever, epilepsy, and chronic rheumatism. They are also used for diuretics, cardiac problems, scurvy, and as an anti-inflammatory agent. Bark is employed as a cardiac stimulant and antifungal agent, and leaves to treat inflammation, helminthesis and scurvy. Seeds are seen as purgative and anti-inflammatory agents, with flowers used as diuretics and as a cholagogue to promote the flow of bile.
Areas of research in this article involve the practicality of various parts of Moringa Oleifera as treatments for cancers, infertility, inflammation, ulcers, and cardiovascular problems. Researchers also investigated its use as an antimicrobial agent.
Conclusions: Moringa Oleifera appears to possess multiple pharmacological possibilities in the conditions listed above. Further clinical evaluation in Western medicine is warranted to determine its therapeutic potential.


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Chemistry and Pharmacology of Moringa oleifera and Moringa con canescens

Author(s): Jadhav SL, SR Sharma, SC Pal, SB Kasture, VS Kasture
Published in: Indian Drugs.   Jan 29, 2000
37 3 139-144

Moringa has many traditional uses that science has
not previously investigated. The many compounds
and their known uses in medicine are presented. It
shows Moringa's pharmaceutical potential, thus
showing the need for further research into the
plant's properties.


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Author(s): Pankaj, T. and A. Kar
Published in: Pharmacological Research.   Oct 29, 1999
41 3 319 319-323
http://www.ncbi.nlm.nih.gov/pubmed/10675284

The role of Moringa Oleifera aqueous leaf extract was studied in adult male and female rats to determine if it was effective in the treatment of thyroid hormone status of animals. The purpose was to see if Moringa extract could be used to regulate thyroid abnormalities in humans.
Leaf power of the Moringa Oleifera was administered to 14 male and 14 female rats. Both groups were divided into control and experimental groups. The Moringa extract was administered with a feeding needle for ten days.

The experiment was completed in two phases, the first on male and female rats and the second with females only. The second administration with females involved higher doses of Moringa Oleifera. Results demonstrate the extract more effective in females than in males.

Results, also, indicate an inhibitory effect of Moringa Oleifera leaf extract in T3 synthesis and/or release. Effects were sex-specific and dosage-specific and more effective in females. T3 is the major thyroid hormone responsible for most metabolic effects of an organism (calorigenesis, oxygen consumption, and maintenance of basal metabolic rate). In the thyroid, T4 is synthesized by the thyroid gland and directly secreted into the blood. T3 is mainly found in peripheral tissues, especially the liver.

Females are more responsive to Moringa Oleifera. This may be related to the fact that females are five times more susceptible to thyroid abnormalities compared to males. A final observation: Higher doses of Moringa Oleifera aqueous leaf abstract may not be safe. Thus, the lower dose may be more useful in the treatment of hyper thyr


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Plant Toxins and Detoxification Methods to Improve Feed Quality of Tropical Seeds

Author(s): Makkar HPS, K Becker
Published in: Asian and Australasian journal of animal sciences.   Oct 20, 1999
12 3 467-480

This paper discusses the various plants which are able to be used as animal feed throughout the world. Of the plants named, the Moringa oleifera is one of the most prominently used for such a purpose. Researchers examined the plant in their laboratory for various chemical components needed in animal nutrition. They then used their findings to examine how such plants could be better used in animal feed.


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Author(s): Kumar S, K Gopar
Published in: Journal of Environmental Science and Health.   Oct 15, 1999
34 4 975-987
http://cat.inist.fr/?aModele=afficheN&cpsidt=1777052

Chemical methods of purifying water are not entirely fool-proof nor completely safe. In this study, Moringa oleifera and other plants were tested at their ability to stop bacterial growth. Researchers chose to use the leaves, and tested their effectiveness at pH levels in which human cells survive. Moringa proved to be about 90% efficient at stopping bacterial growth.


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Author(s): Gupta M, UK Mazumder, S Chakrabarti
Published in: Fitoterapia.   Oct 14, 1999
70 3 244-250
S0367-326X(99)00029-5
http://cat.inist.fr/?aModele=afficheN&cpsidt=1919247

A certain extract of the root of Moringa oleifera proved to have effects on the central nervous system (CNS). When used with seditives and potent painkillers, it increased the drugs' power and duration. Its potential as a depressant warrants further study.


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Role of Moringa oleifera extract in the regulation of thyroid hormone status in adult male and female rats

Author(s): Tahiliani P, A. Kar
Published in: Pharmacological Research.   Aug 23, 1999
31 3 pp 319-323

A study was performed in order to determine the effects of Moringa oleifera leaf extracts on thyroidal hormones. Groups of rats were were orally given either distilled water, the control, or an equal amount of the extract for 10 days. Results showed decreases in the main thyroidal hormone (T3) and increases in its prohormone (T4), but results were only significant in female rats. A proposed explanation is that females are nearly five times as susceptible to thyroid imbalances, but also because of this, the study was repeated with female mice only and the doses changed. The higher dosage also showed the same decrease/increase in hormones, but did not significantly alter other chemical levels being monitored to determine safety of the drug, so the lower dosage was proclaimed safer to use for the treatment of hyperthyroidism.


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Author(s): Guevara AP, C Vargas, H Sakurai, Y Fujiwara, K Hashimoto, M Kozuka, Y Ito, H Tokuda, H Nishino
Published in: Mutation Research/Genetic Toxicology and Environmental Mutag.   Apr 6, 1999
440 2 181-188
10.1016/S1383-5718(99)00025-X
http://www.ncbi.nlm.nih.gov/pubmed/10209341

Niazimicin
"Inhibition of EBV-EA activition was taken as an indication of potential antitumor promoting activity"
Mice were given a skin cancer, the control was left to develop tumors while the variable was treated with the compound niazimicin
"isolates 2, 3, and 8 tested for potential antitumor activity"
Niazimicin is a compound found within the seeds of Moringa oleifera Lam. The researchers decided to study this particular compound, for nothing was known of its possible tumor-inhibiting properties. Niazimicin's effectiveness is compared to that of other chosen compounds.


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